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Volume 5 | No. 7 | July 2016


Commentary
The D-Day of ghrelinJenny Tong, Franck Mauvais-Jarvis

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Commentary
Unforeseen role for glucocorticoids in combinatorial anti-obesity pharmacologyCarmelo Quarta, Christoffer Clemmensen

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Original Research Article
Autonomous interconversion between adult pancreatic α-cells and β-cells after differential metabolic challengesRisheng Ye, Miao Wang, Qiong A. Wang, Stephen B. Spurgin, Zhao V. Wang, Kai Sun, Philipp E. Scherer

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Original Research Article
Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic isletsMichael R. DiGruccio, Alex M. Mawla, Cynthia J. Donaldson, Glyn M. Noguchi, Joan Vaughan, Christopher Cowing-Zitron, Talitha van der Meulen, Mark O. Huising

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Original Research Article
PI3 kinases p110α and PI3K-C2β negatively regulate cAMP via PDE3/8 to control insulin secretion in mouse and human isletsJelena Kolic, Jocelyn E. Manning Fox, Oleg G. Chepurny, Aliya F. Spigelman, Mourad Ferdaoussi, Frank Schwede, George G. Holz, Patrick E. MacDonald

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Original Research Article
Lack of AKT in adipocytes causes severe lipodystrophyAbigail L. Shearin, Bobby R. Monks, Patrick Seale, Morris J. Birnbaum

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Original Research Article
Lipodystrophy and severe metabolic dysfunction in mice with adipose tissue-specific insulin receptor ablationGuifen Qiang, Hyerim Whang Kong, Shanshan Xu, Hoai An Pham, Sebastian D. Parlee, Aaron A. Burr, Victoria Gil, Jingbo Pang, Amy Hughes, Xuejiang Gu, Giamila Fantuzzi, Ormond A. MacDougald, Chong Wee Liew

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Original Research Article
AGPAT2 is essential for postnatal development and maintenance of white and brown adipose tissueKelly M. Cautivo, Carlos O. Lizama, Pablo J. Tapia, Anil K. Agarwal, Abhimanyu Garg, Jay D. Horton, Víctor A. Cortés

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Original Research Article
Metabolic reprogramming through fatty acid transport protein 1 (FATP1) regulates macrophage inflammatory potential and adipose inflammationAmy R. Johnson, Yuanyuan Qin, Alyssa J. Cozzo, Alex J. Freemerman, Megan J. Huang, Liyang Zhao, Brante P. Sampey, J. Justin Milner, Melinda A. Beck, Blossom Damania, Naim Rashid, Joseph A. Galanko, Douglas P. Lee, Matthew L. Edin, Darryl C. Zeldin, Patrick T. Fueger, Brittney Dietz, Andreas Stahl, Ying Wu, Karen L. Mohlke, Liza Makowski

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Original Research Article
G0/G1 Switch Gene 2 controls adipose triglyceride lipase activity and lipid metabolism in skeletal muscleClaire Laurens, Pierre-Marie Badin, Katie Louche, Aline Mairal, Geneviève Tavernier, André Marette, Angelo Tremblay, S. John Weisnagel, Denis R. Joanisse, Dominique Langin, Virginie Bourlier, Cedric Moro

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Original Research Article
Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine exportPhillip J. White, Amanda L. Lapworth, Jie An, Liping Wang, Robert W. McGarrah, Robert D. Stevens, Olga Ilkayeva, Tabitha George, Michael J. Muehlbauer, James R. Bain, Jeff K. Trimmer, M. Julia Brosnan, Timothy P. Rolph, Christopher B. Newgard

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Original Research Article
Limiting glucocorticoid secretion increases the anorexigenic property of Exendin-4Shin J. Lee, Katharina Diener, Sharon Kaufman, Jean-Philippe Krieger, Klaus G. Pettersen, Nino Jejelava, Myrtha Arnold, Alan G. Watts, Wolfgang Langhans

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Original Research Article
Melanocortin-3 receptors in the limbic system mediate feeding-related motivational responses during weight lossMaria Mavrikaki, Clemence Girardet, Andras Kern, Alicia Faruzzi Brantley, Courtney A. Miller, Heather Macarthur, Daniel L. Marks, Andrew A. Butler

Abstract | Graphical abstract | PDF



Original Research Article
PGC-1α expression in murine AgRP7 neurons regulates food intake and energy balanceJonathan F. Gill, Julien Delezie, Gesa Santos, Christoph Handschin

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The 60 Second Metabolist
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Shin J. Lee
ETH Zürich, Switzerland
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Conferences & Events
July 31 −
August 05
2016
Immunological Aspects of Obesity
Big Sky, MT, USA
September
12 − 16
2016
52nd EASD Annual Meeting 2016
Munich, Germany
January
22 − 25
2017
Miami Winter Symposium 2017
Miami, USA
Supported by
Helmholtz Zentrum München
Deutsches Forschungszentrum
f. Gesundheit und Umwelt GmbH
The German Center for
Diabetes Research (DZD)