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Volume 5 | No. 8 | August 2016


Review
Insulin in the nervous system and the mind: Functions in metabolism, memory, and moodSeung-Hwan Lee, Janice M. Zabolotny, Hu Huang, Hyon Lee, Young-Bum Kim

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Original Research Article
An ancestral role for the mitochondrial pyruvate carrier in glucose-stimulated insulin secretionKyle S. McCommis, Wesley T. Hodges, Daniel K. Bricker, Dona R. Wisidagama, Vincent Compan, Maria S. Remedi, Carl S. Thummel, Brian N. Finck

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Original Research Article
miR-125b affects mitochondrial biogenesis and impairs brite adipocyte formation and functionMaude Giroud, Didier F. Pisani, Michael Karbiener, Valentin Barquissau, Rayane A. Ghandour, Daniel Tews, Pamela Fischer-Posovszky, Jean-Claude Chambard, Uwe Knippschild, Tarja Niemi, Markku Taittonen, Pirjo Nuutila, Martin Wabitsch, Stephan Herzig, Kirsi A. Virtanen, Dominique Langin, Marcel Scheideler, Ez-Zoubir Amri

Abstract | PDF



Original Research Article
Lipolysis sensation by white fat afferent nerves triggers brown fat thermogenesisJohn T. Garretson, Laura A. Szymanski, Gary J. Schwartz, Bingzhong Xue, Vitaly Ryu, Timothy J. Bartness

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Original Research Article
Demonstration of a day-night rhythm in human skeletal muscle oxidative capacityDirk van Moorsel, Jan Hansen, Bas Havekes, Frank A.J.L. Scheer, Johanna A. Jörgensen, Joris Hoeks, Vera B. Schrauwen-Hinderling, Helene Duez, Philippe Lefebvre, Nicolaas C. Schaper, Matthijs K.C. Hesselink, Bart Staels, Patrick Schrauwen

Abstract | Graphical abstract | PDF



Original Research Article
mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3Maximilian Kleinert, Benjamin L. Parker, Rima Chaudhuri, Daniel J. Fazakerley, Annette Serup, Kristen C. Thomas, James R. Krycer, Lykke Sylow, Andreas M. Fritzen, Nolan J. Hoffman, Jacob Jeppesen, Peter Schjerling, Markus A. Ruegg, Bente Kiens, David E. James, Erik A. Richter

Abstract | Graphical abstract | PDF



Original Research Article
The F-actin modifier villin regulates insulin granule dynamics and exocytosis downstream of islet cell autoantigen 512Hassan Mziaut, Bernard Mulligan, Peter Hoboth, Oliver Otto, Anna Ivanova, Maik Herbig, Desiree Schumann, Tobias Hildebrandt, Jaber Dehghany, Anke Sönmez, Carla Münster, Michael Meyer-Hermann, Jochen Guck, Yannis Kalaidzidis, Michele Solimena

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Original Research Article
Leptin and insulin engage specific PI3K subunits in hypothalamic SF1 neuronsJong-Woo Sohn, Youjin Oh, Ki Woo Kim, Syann Lee, Kevin W. Williams, Joel K. Elmquist

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Original Research Article
Sexually dimorphic brain fatty acid composition in low and high fat diet-fed miceCarlos Rodriguez-Navas, Eugenia Morselli, Deborah J. Clegg

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Original Research Article
Fibroblast growth factor 21 has no direct role in regulating fertility in female miceGarima Singhal, Nicholas Douris, Alan J. Fish, Xinyao Zhang, Andrew C. Adams, Jeffrey S. Flier, Pavlos Pissios, Eleftheria Maratos-Flier

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Brief Communication
Male-lineage transmission of an acquired metabolic phenotype induced by grand-paternal obesityJennifer E. Cropley, Sally A. Eaton, Alastair Aiken, Paul E. Young, Eleni Giannoulatou, Joshua W.K. Ho, Michael E. Buckland, Simon P. Keam, Gyorgy Hutvagner, David T. Humphreys, Katherine G. Langley, Darren C. Henstridge, David I.K. Martin, Mark A. Febbraio, Catherine M. Suter

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Brief Communication
Optogenetic activation of leptin- and glucose-regulated GABAergic neurons in dorsomedial hypothalamus promotes food intake via inhibitory synaptic transmission to paraventricular nucleus of hypothalamusZesemdorj Otgon-Uul, Shigetomo Suyama, Hiroshi Onodera, Toshihiko Yada

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Brief Communication
The role of autonomic efferents and uncoupling protein 1 in the glucose-lowering effect of leptin therapyHeather C. Denroche, Michelle M. Kwon, Maria M. Glavas, Eva Tudurí, Marion Philippe, Whitney L. Quong, Timothy J. Kieffer

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Brief Communication
Microbially produced glucagon-like peptide 1 improves glucose tolerance in miceTulika Arora, Udo Wegmann, Anup Bobhate, Ying Shiuan Lee, Thomas U. Greiner, Daniel J. Drucker, Arjan Narbad, Fredrik Bäckhed

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Brief Communication
Glucagon receptor gene deletion in insulin knockout mice modestly reduces blood glucose and ketones but does not promote survivalUrsula H. Neumann, Jessica S.S. Ho, Majid Mojibian, Scott D. Covey, Maureen J. Charron, Timothy J. Kieffer

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The 60 Second Metabolist
In this section authors briefly report on their work recently published in Molecular Metabolism.

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Heather C. Denroche
University of British Columbia, Vancouver, Canada
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