Volume 72 | June 2023

Cover Story

Altered amino acid metabolism is increasingly appreciated as a key driver in the pathology of multiple diseases, including metabolic syndrome, cancer, and neurological diseaseSphingolipids (SLs) are synthesized from serine and fatty acyl-CoAs by serine palmitoyltransferase (SPT) and are critical signaling molecules and membrane components that are enriched in the nervous system and retina.


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Jacob D. Covert, Brian A. Grice, Matthew G. Thornburg, Manpreet Kaur, ... Jeffrey S. Elmendorf

Courtney R. Green, Roberto Bonelli, Brendan R.E. Ansell, Simone Tzaridis, ... Marin L. Gantner

Mi Jeong Heo, Ji Ho Suh, Sung Ho Lee, Kyle L. Poulsen, ... Kang Ho Kim

Felix Sternberg, Christina Sternberg, Andreas Dunkel, Taraneh Beikbaghban, ... Elena E. Pohl

D. Liskiewicz, Q. Zhang, C.S. Barthem, M. Jastroch, ... T.D. Müller

Alba Clara Fernández-Rilo, Nicola Forte, Letizia Palomba, Lea Tunisi, ... Luigia Cristino

Thao D.V. Le, Payam Fathi, Amanda B. Watters, Blair J. Ellis, ... Julio E. Ayala

Gabriel Chalhoub, Alina Jamnik, Laura Pajed, Stephanie Kolleritsch, ... Guenter Haemmerle

Brian E. Ford, Shruti S. Chachra, Katrina Rodgers, Tabassum Moonira, ... Loranne Agius

Tobias Ackermann, Hidde R. Zuidhof, Christine Müller, Gertrud Kortman, ... Cornelis F. Calkhoven