Volume 51 | September 2021

Cover Story

AMP-activated protein kinase (AMPK) is a ubiquitously expressed and highly conserved multisubstrate serine and threonine kinase. It is often referred to as an energy sensor of the cell, as cellular energy fluctuations lead to its activation. AMPK is a heterotrimeric protein complex consisting of one α-, β-, and γ-subunit. The α-subunit includes the kinase domain, while the β- and γ-subunits are regulatory in function.


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Mona C. Löffler, Matthias J. Betz, Denis P. Blondin, Robert Augustin, ... Heike Neubauer

Riya Shrestha, Edward Johnson, Frances L. Byrne

Fiona Peris-Sampedro, Iris Stoltenborg, Marie V. Le May, Jeffrey M. Zigman, ... Suzanne L. Dickson

Ziye Chen, Lu Chen, Bo Sun, Dongming Liu, ... Hua Guo

Kaare V. Grunddal, Sarah Tonack, Kristoffer L. Egerod, Jonathan James Thompson, ... Thue W. Schwartz

André L. Queiroz, Sarah J. Lessard, Amanda T. Ouchida, Hygor N. Araujo, ... Leonardo R. Silveira

Sandro Altamura, Katja Müdder, Andrea Schlotterer, Thomas Fleming, ... Martina U. Muckenthaler

Yanyong Xu, Yingdong Zhu, Shuwei Hu, Xiaoli Pan, ... Yanqiao Zhang

N. Vishnu, A. Hamilton, A. Bagge, A. Wernersson, ... H. Mulder

Phil Pickford, Maria Lucey, Roxana-Maria Rujan, Emma Rose McGlone, ... Stephen R. Bloom

G. Tavares, D. Marques, C. Barra, D. Rosendo-Silva, ... P. Matafome

Philipp Rhein, Eric M. Desjardins, Ping Rong, Danial Ahwazi, ... Kei Sakamoto

Nicolas O. Jørgensen, Rasmus Kjøbsted, Magnus R. Larsen, Jesper B. Birk, ... Jørgen F.P. Wojtaszewski

 

Pengfei Liu, Matthew Dodson, Hui Li, Cody J. Schmidlin, ... Donna D. Zhang

Anna E. Garcia Whitlock, Jamarie Sostre-Colón, Matthew Gavin, Niels D. Martin, ... Paul M. Titchenell