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Histaminergic neurons are confined to the tuberomammillary nucleus (TMN) in the posterior hypothalamus and provide the sole source of neuronal histamine to the brain. These neurons are identified based on the expression of histidine decarboxylase (HDC), the enzyme required to convert l-histidine into histamine. HDC neurons form a crucial part of the ascending arousal system and have well-established roles in regulating sleep and wakefulness.
Natalie J. Michael, Alexandre Caron, Charlotte E. Lee, Carlos M. Castorena, ... Joel K. Elmquist
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The 60 Second Metabolist
In this section authors briefly report on their work recently published in Molecular Metabolism.
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