Cover Story Current Issue

Cancer cachexia is a systemic metabolic dysfunction that affects more than 80% of pancreatic cancer patients and is the leading cause of death in 22%–30% of all cancers. Because the cancer spread beyond the pancreas at the time of diagnosis, only about 20% of patients are candidates for surgery. Pancreatic cancer's aggressiveness destabilizes whole-body homeostasis by dismantling the normal network of organs crosstalk. This miss-communication favors the tumor progression during cancer cachexia, which is characterized by devastating body weight lossmuscle atrophy, fat wasting, decreased appetite. The molecular mechanisms underlying these metabolic cues are still being investigated.

Mengistu Lemecha, Jaya Prakash Chalise, Yuki Takamuku, Guoxiang Zhang, ... Keiichi Itakura

Full text

 

Current Issue

Allyson K. Palmer, Tamar Tchkonia, James L. Kirkland

Karla F. Leavens, Juan R. Alvarez-Dominguez, Linda T. Vo, Holger A. Russ, Audrey V. Parent

Nitin Patil, Orla Howe, Paul Cahill, Hugh J. Byrne

Sierra A. Nance, Lindsey Muir, Carey Lumeng

Soichiro Sonoda, Sara Murata, Haruyoshi Yamaza, Ratih Yuniartha, ... Takayoshi Yamaza

Brecht Attema, Aafke W.F. Janssen, Deborah Rijkers, Evert M. van Schothorst, ... Sander Kersten

Hao Sun, Sunmi Seok, Hyunkyung Jung, Byron Kemper, Jongsook Kim Kemper

Sophie Tritschler, Moritz Thomas, Anika Böttcher, Barbara Ludwig, ... Fabian J. Theis

Angelique Cercillieux, Joanna Ratajczak, Magali Joffraud, José Luis Sanchez-Garcia, ... Carles Canto

Daniel J. Han, Rukhsana Aslam, Paraish S. Misra, Felix Chiu, ... Cynthia T. Luk

Jo E. Lewis, Orla RM. Woodward, Danaé Nuzzaci, Christopher A. Smith, ... Frank Reimann

Adam J. Rauckhorst, Nicholas Borcherding, Daniel J. Pape, Alora S. Kraus, ... Eric B. Taylor

Anfal Al-Mass, Pegah Poursharifi, Marie-Line Peyot, Roxane Lussier, ... Marc Prentki

Eliza Bollinger, Matthew Peloquin, Jenna Libera, Bina Albuquerque, ... Rachel J. Roth Flach

Mengistu Lemecha, Jaya Prakash Chalise, Yuki Takamuku, Guoxiang Zhang, ... Keiichi Itakura

Gommaar D'Hulst, Evi Masschelein, Katrien De Bock

Gandhari Maity-Kumar, Lisa Ständer, Meri DeAngelis, Sooyeon Lee, ... Timo D. Müller

Hanyue Li, Yu Yuan, Hongying Chen, Hongwei Dai, Jie Li

Jisun So, Solaema Taleb, Jamie Wann, Olivia Strobel, ... Hyun Cheol Roh

Yvo J.M. op den Kamp, Anne Gemmink, Marlies de Ligt, Bas Dautzenberg, ... Patrick Schrauwen

Yue Deng, Jacob E. Dickey, Kenji Saito, Guorui Deng, ... Huxing Cui

Tamadher A. Alghamdi, Nicole A.J. Krentz, Nancy Smith, Aliya F. Spigelman, ... Patrick E. MacDonald

Takumi Kitamoto, Yun-Kyoung Lee, Nishat Sultana, Hitoshi Watanabe, ... Domenico Accili

Luis Rodrigo Cataldo, Qian Gao, Lidia Argemi-Muntadas, Ondrej Hodek, ... Thomas Moritz

Mikhaela B. Slavin, Rita Kumari, David A. Hood

 

Baraa Altaha, Marjolein Heddes, Violetta Pilorz, Yunhui Niu, ... Silke Kiessling

Yang Li, Shuting Yang, Shuying Yang

Qiying Ye, Jeremiah Nunez, Xiaobing Zhang

Yun-Kyoung Lee, Wen Du, Yaohui Nie, Bryan Diaz, ... Sandro Belvedere

Anna Juliane Vesting, Alexander Jais, Paul Klemm, Lukas Steuernagel, ... F. Thomas Wunderlich

 

Huiyuan Zheng, Lorena López-Ferreras, Jean-Phillipe Krieger, Stephen Fasul, ... Linda Rinaman

Tina Zimmermann, Leo Thomas, Tamara Baader-Pagler, Peter Haebel, ... Robert Augustin

Byong Seo Park, Dasol Kang, Kwang Kon Kim, Bora Jeong, ... Byung Ju Lee

Brent A. McLean, Chi Kin Wong, M Golam Kabir, Daniel J. Drucker

Katrine D. Galsgaard, Emilie Elmelund, Christian D. Johansen, Anna B. Bomholt, ... Nicolai J. Wewer Albrechtsen

Johana Coronel, Jianshi Yu, Nageswara Pilli, Maureen A. Kane, Jaume Amengual

Kim Eerola, Francesco Longo, Thomas M. Reinbothe, Jennifer E. Richard, ... Karolina P. Skibicka

Byung-Jun Sung, Sung-Bin Lim, Won-Mo Yang, Jae Hyeon Kim, ... Moon-Kyu Lee

Ilaria Coppola, Bas Brouwers, Leanne Walker, Ceyhun Alar, ... John W.M. Creemers

Yong Kyung Kim, Jay A. Walters, Nicole D. Moss, Kristen L. Wells, ... Howard W. Davidson

Miki Igarashi, Tetsuhiko Hayakawa, Haruka Tanabe, Keita Watanabe, ... Ikuo Kimura

Liora S. Katz, Carmen Argmann, Luca Lambertini, Donald K. Scott

M. Villarreal-Salazar, A. Santalla, A. Real-Martínez, G. Nogales-Gadea, ... T. Pinós

Shawn J. Geffken, Sohyun Moon, Catherine O. Smith, Sharon Tang, ... Weikang Cai

Jian Qiu, Martha A. Bosch, Todd L. Stincic, Avery C. Hunker, ... Martin J. Kelly

Ruiyue Qiu, Kristina Alikhanyan, Nadine Volk, Oriana Marques, ... Martina U. Muckenthaler

Svenia Schmid, Barbara Heim-Kupr, Joaquín Pérez-Schindler, Shivani Mansingh, ... Christoph Handschin

Ernesto Pena Calderin, Jing-Juan Zheng, Nolan L. Boyd, Lindsey McNally, ... Jason Hellmann

Bin Yang, Vasily M. Gelfanov, Kimberley El, Alex Chen, ... Brian Finan

Xiaojie Peng, Shuze Chen, Ying Wang, Ming Jin, ... Wei Gong

Vance L. Albaugh, Yanlin He, Heike Münzberg, Christopher D. Morrison, ... Hans-Rudolf Berthoud

2021 impact factor: 8.568

Here is a video of Vimeo. When the iframes is activated, a connection to Vimeo is established and, if necessary, cookies from Vimeo are also used. For further information on cookies policy click here.