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At the turn of the 19th century, Ivan Pavlov and others established that the secretion of pancreatic juice is induced upon entry of acidic chyme into the duodenum, and that this pancreatic secretion is accelerated by infusion of hydrochloric acid (HCL) into the stomach. Pavlov hypothesized that secretion of pancreatic juice is induced via a neuronal reflex; however, pancreatic secretion prevailed in dogs following denervation of the intestinal vagal and splanchnic nerves, indicating that pancreatic secretion must be mediated by another, as yet unknown, mechanism.

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Current Issue

Margo P. Emont, Adam L. Essene, Anton Gulko, Nadejda Bozadjieva-Kramer, ... Evan D. Rosen

Amanda K. Casey, Nathan M. Stewart, Naqi Zaidi, Hillery F. Gray, ... Kim Orth

Celso Pereira Batista Sousa-Filho, Natasa Petrovic

Timo D. Müller, Alice Adriaenssens, Bo Ahrén, Matthias Blüher, ... Matthias H. Tschöp

Stephen P. Ashcroft, Amy M. Ehrlich, Krzysztof Burek, Logan A. Pendergrast, ... Juleen R. Zierath

Liran Xu, Chao Yang, Kaidan Pang, Ying Zhang, ... Shengpeng Wang

Kentaro Kaneko, Weisheng Lu, Yong Xu, Alexei Morozov, Makoto Fukuda

Jordan Wean, Allison Ho Kowalsky, Rhianna Laker, Sarah Will, ... Randy J. Seeley

Anne-Marie Lundsgaard, Rita Del Giudice, Josephine M. Kanta, Mark Larance, ... Bente Kiens

Tara L. MacDonald, Birgitta Ryback, Jéssica Aparecida da Silva Pereira, Siying Wei, ... Peng Yi

Johannes Reiner, Nooshin Mohebali, Jens Kurth, Maria Witte, ... Georg Lamprecht

Shifeng Wang, Yuanxu Cui, Limei Wang, Chun Feng, ... Qiang Zhang

L. Stilgenbauer, Q. Chen, D. Pungi, N. James, ... M. Sadagurski

Agnieszka Podraza-Farhanieh, Rosa Spinelli, Federica Zatterale, Annika Nerstedt, ... Ulf Smith

Articles in Press

Michael E. Ponte, John C. Prom, Mallory A. Newcomb, Annabelle B. Jordan, ... E. Matthew Morris

Long J. Shao, Fathima Elizondo, Feng Gao, Rabie Habib, ... Kai Sun

Yunhan Zou, Jiaoxiang Wu, Sheng Cheng, Daqing Cheng, ... Bo Han

Caitlyn E. Bowman, Michael D. Neinast, Ryo Kawakami, Nicholas Forelli, ... Zolt Arany

Jonathan Trujillo-Viera, Mona C. Wittmann, Daniel Lam, Yang Shen, ... Bradford Hamilton

Natalia Prudente de Mello, Michelle Tamara Berger, Kim A. Lagerborg, Yingfei Yan, ... Kenneth Allen Dyar

Mattias Bergentall, Valentina Tremaroli, Chuqing Sun, Marcus Henricsson, ... Fredrik Bäckhed

Jonathan D. Douros, Aaron Novikoff, Barent DuBois, Rebecca Rohlfs, ... Patrick J. Knerr

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12th Helmholtz 
Diabetes Conference 

22-24. Sep, Munich

You are what you eat

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