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The Ile191Val is a partial loss-of-function variant of the TAS1R2 sweet-taste receptor and is associated with reduced glucose excursions in humans

Proteomic quantitative study of dorsal root ganglia and sciatic nerve in type 2 diabetic mice

URAT1-selective inhibition ameliorates insulin resistance by attenuating diet-induced hepatic steatosis and brown adipose tissue whitening in mice

Requirement of Cavin-2 for the expression and stability of IRβ in adequate adipocyte differentiation

Antimetabolic cooperativity with the clinically approved l-asparaginase and tyrosine kinase inhibitors to eradicate CML stem cells

Neuropeptide Y1 receptor antagonism protects β-cells and improves glycemic control in type 2 diabetes

Plasma triacylglycerols are biomarkers of β-cell function in mice and humans

miR-126 contributes to the epigenetic signature of diabetic vascular smooth muscle and enhances antirestenosis effects of Kv1.3 blockers

Novel noncoding RNA CircPTK2 regulates lipolysis and adipogenesis in cachexia

Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulin

Ablation of glucokinase-expressing tanycytes impacts energy balance and increases adiposity in mice

Endothelial BBSome is essential for vascular, metabolic, and retinal functions

Nuclear Receptor CoRepressors, NCOR1 and SMRT, are required for maintaining systemic metabolic homeostasis

Loss of chemerin triggers bone remodeling in vivo and in vitro

Cyp2c-deficiency depletes muricholic acids and protects against high-fat diet-induced obesity in male mice but promotes liver damage